HELIXPrep › Plant, Animal and Microbial Biotechnology › Animals
Module 5.2 · Topic 4
Module 5.2 · Topic 4
A term from Immunology, finally explained
Back in Immunology, monoclonal antibodies were described as coming from "a single cloned B cell lineage," produced deliberately via "hybridoma technology" — a term named but never actually explained. Here's the mechanism behind it.
Antibody-producing B cells have a limited lifespan in culture. Myeloma (cancerous) cells can divide indefinitely but don't produce a useful antibody. Fusing the two together — what does the resulting hybrid cell gain?
A hybridoma is created by fusing:
Create a free account to track your progress, earn XP, and unlock every free module on HELIXPrep.
Create Free Account →