HELIXPrep › Plant, Animal and Microbial Biotechnology › Animals
Module 5.2 · Topic 6
Module 5.2 · Topic 6
How a mammary gland cell became an entire sheep
Dolly the sheep, born in 1996, was created from the nucleus of an ordinary, already-differentiated mammary gland cell — a cell that, sitting in an udder, could never have become an organism on its own. Something reset it.
A differentiated somatic cell's nucleus is transferred into an egg cell whose own nucleus has been removed. Does the resulting reconstructed cell behave like the original somatic cell, or like a fertilised egg?
Somatic cell nuclear transfer (SCNT), the technique used to create Dolly the sheep, works by:
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